e. state or locally hired distributors) for further distribution to small providers, and the estimated proportion of doses NVP-BGJ398 solubility dmso that were administered in public sites. Two factors were related to existing

health infrastructure: the maximum number of ship-to-sites had a positive association with coverage, and the percentage of medically underserved population a negative association. Coverage was also negatively associated with population factors including the percentage of the population that will not visit a medical doctor because of cost, the number of vehicles per capita, and the percentage of population under 18 years old. For high-risk adults, two supply chain processes were positively associated with uptake: the percentage of doses shipped to “general public” locations, and the use of pharmacy and retail locations for vaccination; and one, the expansion of vaccination to the general public by December 4th, was negatively associated. Coverage was positively associated

with population and health related factors: percentage of women with a Pap smear, past seasonal influenza FGFR inhibitor vaccination, and percentage of population that is American Indian. Two infrastructure factors were associated: the proportion of the population medically underserved (negatively) and the maximum number of ship-to-sites (positively). We sought to identify factors related to vaccination program decisions and processes that may have facilitated or hindered vaccine Libraries uptake for two target groups for vaccination: children and high-risk adults. Several supply chain and system factors were associated with vaccination coverage of children and of high-risk adults. With the exception of the maximum number of ship-to sites, a factor that was also associated with overall adult coverage [3], factors associated with coverage of children and of high-risk Thymidine kinase adults did not overlap. Additionally, factors not related to program decisions such as health-seeking behaviors and population characteristics

were also associated with state-to-state variation, as would be expected given baseline variation in vaccination coverage for recommended vaccines [4] and the variety of factors associated with vaccinations, both for high-risk individuals [15], [17], [18] and [33] and children [13] and [14]. Several findings were related to the type of providers or locations to which vaccine was directed. For children, having a focus on school vaccination was associated with higher coverage (five of the six states that achieved the highest coverage in children implemented statewide school vaccination programs [2] and [6]), as was distribution to public sites. Public sites can include schools, but also locations such as mass clinics run by health departments. For high-risk adults, more distribution to providers with a broad base of access (including pharmacies, primary care providers, county health departments, etc.) was associated with higher coverage.