The transcripts of RsMPK2 were rapidly accumulated at high levels when R. soongorica was subjected to dehydration, salinity conditions and treatment with abscisic acid or hydrogen peroxide. Growth analysis of NVP-LDE225 Escherichia
coil (srl::Tn10) cells transformed with pPROEXHT-RsMPK2 showed that the expression products of RsMPK2 do not act as an osmoprotectant. But, the inhibition of RsMPK2 expression by the inhibitor U0126 induced a decrease of antioxidant enzyme activity under stresses, indicating that RsMPK2 is involved in the regulation of the antioxidant defense system in the response to stress signaling. (C) 2010 Elsevier Masson SAS. All rights reserved.”
“PURPOSE: To determine in a longitudinal study whether there is correlation between videokeratography and clinical signs of keratoconus that might be useful to practicing clinicians.
SETTING: Cornea-Genetic Eye Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
METHODS: Eyes grouped as keratoconus, early keratoconus, keratoconus suspect, or normal based on clinical signs and videokeratography were examined at baseline and followed for 1 to VX-809 order 8 years. Differences in quantitative videokeratography indices and the progression rate were evaluated. The quantitative indices were central keratometry (K), the inferior-superior (I-S)
value, and the keratoconus percentage index (KISA). Discriminant analysis was used to estimate the classification rate using learn more the indices.
RESULTS: There were significant differences at baseline between the normal, keratoconus-suspect, and early keratoconus groups in all indices; the respective means were central K: 44.17 D, 45.13 D, and 45.97 D; I-S: 0.57, 1.20, and 4.44; log(KISA): 2.49, 2.94, and 5.71 (all P<.001 after adjusting for covariates). Over a median follow-up of 4.1 years, approximately 28% in the keratoconus-suspect group progressed to early keratoconus or keratoconus and 75% in the early keratoconus group progressed to keratoconus. Using all 3 indices and age, 86.9% in the normal group, 75.3% in the early keratoconus group,
and 44.6% in the keratoconus-suspect group could be classified, yielding a total classification rate of 68.9%.
CONCLUSIONS: Cross-sectional and longitudinal data showed significant differences between groups in the 3 indices. Use of this classification scheme might form a basis for detecting subclinical keratoconus.”
“The effect of annealing within the incommensurate phase on the dielectric function epsilon of the TlInS2 single crystals has been investigated. It is shown that the effect of annealing is very close to the effect of doping by electrically active impurity La. The inference is made that the correlation between observed effects in annealed and doped crystals is conditioned by the internal electric fields induced by the activation (polarization) of native defects during the annealing procedure.