This study examines the efficacy of the excision and ablation strategy of TLS using the 532-nm pulsed potassium-titanyl-phosphate (KTP) laser as an alternative to the conventional carbon dioxide (CO2) laser in treating T1a glottis carcinoma. The tumor was excised using KTP laser, followed by circumferential ablation of the mucosa surrounding the surgical margin in a non-contact

manner using the KTP laser. Local control was obtained in 22 of 24 patients (91.7 %). Mean scores on Voice-Related Quality of Life questionnaire (V-RQOL) and the Proteasome inhibitor Voice Handicap Index-10 (VHI-10) were 81.0 and 6.2, respectively. A highly significant correlation was observed between scores of V-RQOL and adjusted VHI-10 (r = 0.96). TLS with a KTP laser for early glottic carcinoma achieved acceptable local control and postoperative voice comparable to those with a CO2 laser reported in the literature, suggesting that the procedure

based on an excision and ablation strategy can be considered oncologically and functionally acceptable for this lesion.”
“Revision rhinoplasties are extremely difficult to perform even for the surgeons mastering nasal surgery. In fact, they must be skilled at adapting surgical strategies to the anatomical changes induced by primary rhinoplasty.

We herein describe an original technique using an auricular cartilage graft after 6 revision rhinoplasties.

The aforementioned graft succeeded in improving tip support, GW2580 concentration Selleck ACP-196 correct external nasal valve dysfunction and alar pinch, and providing tip definition, projection, and ptosis.

In our opinion, rainbow graft is a safe approach in case of severe nasal structural deficiencies, improving both the functional and esthetic results in revision rhinoplasties.”
“Purpose of review

Sudden death is a leading cause of death in industrialized nations. Sudden death in children represents a relatively small proportion of sudden death in the population, but has devastating effects

on families and communities, and often attracts significant attention.

Recent findings

Several recent studies show that a portion of previously unexplained sudden death in children is due to cardiac conditions which are potentially identifiable by ‘molecular autopsy’ or investigation of family members. As some of these conditions that may present with sudden death can be detected by ECG, the controversial role of screening asymptomatic children will be discussed, as will the question of increased risk associated with stimulant medications. Recent pharmacologic and nonpharmacologic advancements for those with identifiable conditions at increased risk of sudden death will be reviewed.

Summary

Recent developments have refined our understanding of the various causes of sudden death in children.