Furthermore, hypersomnia was not associated with overeating while “getting too much sleep” showed a positive association with overeating. Conclusions: Hypersomnia needs to be evaluated using a strict definition. Otherwise, it leads to

an overestimation of this symptom in major depressive episode subjects and to a false association with overeating. (C) 2014 Elsevier Inc. All rights reserved.”
“In France, in 2005, there were approximately 16,000 new cases of head and neck cancer. These cancers have an unfavourable prognosis: the survival this website rates at 3 and 10 years are 50% and 10% respectively. The consumption of alcohol and tobacco is the most important risk factor; in some countries HPV infection was identified as a risk factor of head and neck tumours. Furthermore, a poor oral hygiene seems to raise this risk. We found many decay and periodontium problems in patients with an upper aerodigestive tract cancer. An evaluation of dental state is necessary before any cancer treatment. Treatments by radiotherapy engender noxious effects: hypocellular, hypovascularization, hypoxie of the irradiated tissues, which lead to immediate and chronically oral complications such as mucositis, fibrosis,

xerostomia, decay, or osteoradionecrosis. An oral follow-up of these patients can prevent these complications, or reduce the severity of oral complications, and promote a good oral state. (C) 2015 Societe francaise de radiotherapie selleck chemical oncologique (SFRO). Published by Elsevier Masson SAS. All rights reserved.”
“Objective: To assess the prognostic value of the pro-apoptotic, but also cell growth-inducing molecule soluble tumor necrosis factor-like weak inducer of apoptosis (sTWEAK) in heart

failure (HF).\n\nMethods: We assayed sTWEAK levels in 351 patients with advanced HF (non-ischemic: 130, ischemic: 221). During a median follow-up of 4.9 years, 195 patients (56%) died.\n\nResults: sTWEAK concentrations were associated with extended survival in patients with non-ischemic (P = 0.022), but not with ischemic HF (P = 0.82). The inverse association in non-ischemic HF remained significant in a multivariable Cox regression ZD1839 model (P = 0.025) with a hazard ratio of 0.40 (95% confidence interval: 0.21-0.77) comparing the third to the first tertile (P = 0.007).\n\nConclusion: Low sTWEAK levels independently predict mortality in advanced non-ischemic HF. sTWEAK-induced proliferation of cardiomyocytes may explain its impact on suvival. The different prognostic value of sTWEAK in ischemic and non-ischemic HF may point towards distinct pathogenic pathways determining the course of disease. (C) 2010 Elsevier Ireland Ltd. All rights reserved.”
“The synaptosomal plasma membrane Ca2+-ATPase (PMCA) plays an essential role in regulating intracellular Ca2+ concentration in brain.